Final answer:
A weakness of Microsoft Excel relative to other spreadsheet software is the lack of advanced statistical analysis tools.
Step-by-step explanation:
A weakness of Microsoft Excel relative to other spreadsheet software is the lack of advanced statistical analysis tools. While Excel does have some statistical functions, it is often considered less robust in this area compared to other programs like R or Python. These alternate software packages have more specialized statistical functions and capabilities, making them better suited for advanced statistical analysis tasks.