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Master Transcription Regulators: 3 examples, make what possible control what newtowrk and

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Master transcription regulators are proteins that control the rate of transcription of genes. They bind to specific DNA sequences called regulatory elements, which are usually found in the promoter region of genes. By binding to these regulatory elements, master transcription regulators can either enhance or repress the transcription of genes.

Step-by-step explanation:

Master transcription regulators are proteins that control the rate of transcription of genes. They bind to specific DNA sequences called regulatory elements, which are usually found in the promoter region of genes. By binding to these regulatory elements, master transcription regulators can either enhance or repress the transcription of genes. Here are three examples of master transcription regulators:

  1. p53: p53 is a master transcription regulator that plays a critical role in regulating cell cycle progression and preventing tumor formation. It acts as a tumor suppressor by activating the transcription of genes involved in cell cycle arrest, DNA repair, and apoptosis.
  2. CREB: CREB (cAMP response element-binding protein) is a master transcription regulator that is involved in various cellular processes, including memory formation and neuronal development. It binds to specific DNA sequences called cAMP response elements (CREs) and regulates the transcription of target genes.
  3. Estrogen receptor: Estrogen receptor is a master transcription regulator that binds to estrogen response elements (ERE) in the DNA and regulates the transcription of genes involved in various processes, such as reproduction and cell growth.

These master transcription regulators control gene expression by binding to specific DNA sequences and recruiting other proteins, such as coactivators or corepressors, to the promoter region of genes. This recruitment of proteins can either enhance or repress the activity of RNA polymerase, the enzyme responsible for transcribing DNA into RNA.

Keywords: master transcription regulators, p53, CREB, estrogen receptor, gene expression, DNA sequences, promoter region, RNA polymerase

User Kendrea
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