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List some genetic disorders that have been linked to X

User Kessy
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Final answer:

Genetic disorders linked to the X chromosome include red-green color blindness, Types A and B hemophilia, and some forms of muscular dystrophy. These disorders are more common in males as they only need one recessive mutant X allele to be affected, while females can be carriers without showing symptoms.

Step-by-step explanation:

Several genetic disorders have been linked to the X chromosome and are typically referred to as X-linked disorders. These genetic disorders are more likely to affect males because they have only one X chromosome, and a single recessive mutant X allele is enough to express the disorder. Some common examples of X-linked genetic disorders include:

  • Red-green color blindness: This is an inability to distinguish between red and green colors and is one of the most common forms of color blindness.
  • Hemophilia: Types A and B hemophilia are blood-clotting disorders that are caused by mutations in the genes responsible for clotting factors.
  • Muscular dystrophy: Some forms of muscular dystrophy, such as Duchenne and Becker muscular dystrophy, are caused by mutations in the dystrophin gene located on the X chromosome.

Females can be carriers of these disorders if they inherit one recessive allele and one dominant allele, which typically results in them being unaffected due to the presence of a normal allele. However, they can pass the trait to their sons, who would then exhibit the trait if they inherit the recessive allele.

User Abinesh Joyel
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