Question

Define mRNA editing and name common 2 types

Answer 1

mRNA editing involves changes to the coding sequence of mRNA. Common types include substitution editing and insertion/deletion editing.

Step-by-step explanation:

RNA editing is a post-transcriptional modification process that involves changes to the coding sequence of mRNA. It can result in the insertion, deletion, or substitution of nucleotides in mRNA. There are two common types of mRNA editing: substitution editing and insertion/deletion editing.

1. Substitution editing: In substitution editing, specific nucleotides are altered in the mRNA sequence. This can lead to changes in the amino acids incorporated into the protein during translation. One example of substitution editing is the APOB protein in humans, where mRNA editing results in two different forms of the protein with distinct functions.
2. Insertion/deletion editing: In insertion/deletion editing, nucleotides are either added or removed from the mRNA sequence. This can affect the reading frame and the resulting protein. The best-known example of insertion/deletion editing is found in mitochondria, where almost all pre-mRNAs are edited.