Final answer:
The statement "The main route of entry for biological agents is through ingestion or penetration" is True. Biological agents typically gain entry to the body through ingestion or penetration via the skin, mucous membranes, and other routes.
Step-by-step explanation:
The main route of entry for biological agents is through ingestion or penetration. This statement is true.
Biological agents, such as pathogens, commonly enter the body either by being ingested through the gastrointestinal tract or by penetrating the protective barriers of the skin or mucous membranes.
Ingestion occurs when microorganisms are taken in with food or water, while penetration can occur through breaches in the skin such as wounds, insect bites, or medical injections (parenteral route).
The skin and mucous membranes are major portals of entry for pathogens, providing access to host tissue.
Other entry points include the respiratory mucosa and the mucosa of the eyes and genitalia. Therefore, exposure to pathogens can potentially lead to infection if the organism can bypass these defense mechanisms and gain entry into the host.
Hence, the correct answer is: True.