Question

______ is huge cell derived from the fusion of as many as 50 monocytes; concentrated in the endosteum; functions in resorption, the breakdown of bone extracellular matrix.

Answer 1

Osteoclasts are large, multinucleated cells derived from up to 50 monocytes that are responsible for breaking down bone tissue and dissolving its minerals.

Step-by-step explanation:

The huge cell derived from the fusion of as many as 50 monocytes, which is concentrated in the endosteum and functions in resorption, the breakdown of bone extracellular matrix, is known as osteoclast. Osteoclasts are responsible for the bone tissue resorption process which includes dissolving the minerals in bone and releasing them into the blood. These multinucleated cells are crucial for the dynamic balancing act of bone remodeling as they continually break down old bone, while osteoblasts build new bone.