28.4k views
4 votes
What are the three effects of sympathetic stimulation on ventricular contraction and relaxation?

1 Answer

5 votes

Final answer:

Sympathetic stimulation affects ventricular function by increasing contractility and heart rate, and improving ventricular filling, collectively enhancing cardiac output.

Step-by-step explanation:

The three effects of sympathetic stimulation on ventricular contraction and relaxation are:

Increased Contractility: Sympathetic stimulation releases norepinephrine (NE) and epinephrine, which bind to alpha and beta receptors on the cardiac muscle cells. This increases the metabolic rate and force of contraction, resulting in a higher stroke volume (SV) and a lower end-systolic volume (ESV). Enhanced Heart Rate: NE also shortens the repolarization period, quickening the rate of depolarization and contraction, which elevates the heart rate (HR). Improved Ventricular Filling: Sympathetic stimulation to the venous system increases venous return, contributing to better ventricular filling and end-diastolic volume (EDV), thereby enhancing preload and allowing for a more forceful contraction.

These actions collectively increase the efficacy of cardiac output during periods of heightened demand, such as during exercise or stress.

User Roryhewitt
by
7.8k points