Final answer:
The major difference in philosophy behind evolution and creationism is the acceptance of a literal interpretation of religious texts.
Step-by-step explanation:
The major difference in philosophy behind evolution and creationism is B) The acceptance of a literal interpretation of religious texts. Evolution is based on scientific evidence and the understanding of natural selection as a major mechanism for species change over time. Creationism, on the other hand, relies on a literal interpretation of religious texts and the belief that all species were specially created by a deity.