Final answer:
1895 is significant in cinematic history because it marked the first public film screening conducted by the Lumière brothers. D.W. Griffith was responsible for the birth of Hollywood with his film "Birth of a Nation" in 1922.
Step-by-step explanation:
The significance of 1895 in cinematic history is that it marked the first public film screening by the Lumière brothers using their invention, the Cinematograph. On December 28, 1895, in Paris, the Lumière brothers showcased ten one-minute films, including "Workers Leaving the Lumière Factory" and "The Arrival of a Train at La Ciotat." This event marked the birth of cinema as a public form of entertainment. D.W. Griffith, on the other hand, is associated with the birth of Hollywood, as he directed and produced the first major full-length film, "Birth of a Nation," which was released in 1922.