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The enzyme that catalyzes the initial processing of miRNAs in the nucleus is:

A. Drosha.
B. Dicer.
C. Argonaute.
D. RNase A.

1 Answer

4 votes

Final answer:

Drosha is the enzyme that catalyzes the initial processing of miRNAs in the nucleus.

Step-by-step explanation:

The enzyme that catalyzes the initial processing of miRNAs in the nucleus is Drosha. MiRNAs are small (~23 nt) RNA molecules that control gene expression at the post-transcriptional level. They are synthesized from hairpin precursors and processed by two duplex-specific endonucleases, Drosha and Dicer. Drosha catalyzes the cleavage of the primary miRNA transcript, while Dicer is responsible for the production of mature miRNAs.

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