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A rejuvenation solution may be used up to how many days following expiration of a red cell unit?

A) 7 days
B) 14 days
C) 21 days
D) 28 days

User Nachokk
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1 Answer

5 votes

Final answer:

Rejuvenation solutions extend the usability of expired red blood cell units, but the time frame can vary. Reticulocytes mature into erythrocytes, which survive approximately 120 days in circulation before being removed by phagocytic cells.

Step-by-step explanation:

The question is related to the storage and viability of red blood cell units after their expiration date using a rejuvenation solution. Rejuvenation solutions are used to restore the functionality of red blood cells that have surpassed their storage life. However, there is a limit to how long after expiration these solutions can be used. The specific time frame given in the options provided can vary depending on regulatory guidelines and product specifications, and the correct answer may depend on local regulations or the instructions of the specific rejuvenation solution in use.

Reticulocytes are immature red blood cells released into the bloodstream, where they then mature into erythrocytes. Erythrocytes circulate for an average of 120 days before being phagocytosed by macrophages in the spleen, liver, and bone marrow. The hemoglobin from degraded erythrocytes is further processed into different components, which is an important aspect in understanding the life cycle and degradation of red blood cells.

User Olle Kyrychenko
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