Final answer:
Hypothermia, inadequate production of clotting factors, and thrombocytopenia are factors that can worsen bleeding by reducing the blood's ability to clot.
Step-by-step explanation:
Factors that may reduce the blood's natural ability to clot and worsen internal or external bleeding include hypothermia, an inadequate production of clotting factors, and thrombocytopenia (an insufficient number of platelets). Hypothermia can slow down enzymatic reactions necessary for the clotting process. In situations like hemophilia, there is an inadequate production of clotting factors such as factor VIII or IX, leading to excessive bleeding. Finally, thrombocytopenia, which is a condition where there is a low platelet count, also makes it difficult for blood to form clots properly, causing excessive bleeding from even minor wounds.