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All of the following are sources of serum alkaline phosphatase except

a) Bone
b) Liver
c) Kidney
d) Heart

1 Answer

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Final answer:

The source of serum alkaline phosphatase not listed among the options is the heart. Alkaline phosphatase is mainly found in the liver, bone, and placental tissue but is not significantly present in heart tissue.

Step-by-step explanation:

The source of serum alkaline phosphatase that is not listed among the options provided is heart. Serum alkaline phosphatase (ALP) is an enzyme that is mainly found in the cells lining the biliary ducts of the liver, in bone, and in placental tissue. This enzyme is involved in the dephosphorylation process, which is important for many biological functions. Elevated levels of ALP can be found in conditions such as bile duct obstruction, liver diseases, and bone disorders, or during periods of increased bone turnover, such as growth or certain bone diseases like Paget's disease.

ALP is not significantly present in heart tissue, making option d) Heart the correct answer to this question. The liver and bone are the main sources of ALP in the serum, with the liver enzyme being more responsive to hepatobiliary conditions and the bone isoenzyme reflecting osteoblastic activity. The kidney can also express ALP.

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