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Which of the following cardiac biomarkers rises within 1-3 hours after chest pain, peaks in 2-6 hours, and normal within 24 hours?

a) Troponin
b) Myoglobin
c) Creatine kinase-MB (CK-MB)
d) Brain natriuretic peptide (BNP)

User Aabdulahad
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1 Answer

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Final answer:

Myoglobin is the cardiac biomarker that rises within 1-3 hours after chest pain, peaks in 2-6 hours, and normalizes within 24 hours.

Step-by-step explanation:

Among the cardiac biomarkers listed, myoglobin is the one that rises within 1-3 hours after chest pain, peaks in 2-6 hours, and returns to normal within 24 hours. Myoglobin is a heme-protein that stores oxygen in muscle cells and releases it when needed. Because it is released quickly from damaged heart muscle following a myocardial infarction (MI), it can serve as an early marker for acute MI. However, it is not as specific to cardiac tissue as other markers, such as troponin or Creatine kinase-MB (CK-MB).

CK-MB, an isoenzyme of Creatine phosphokinase (CPK), is also a marker for myocardial infarction, but unlike myoglobin, it maintains a higher concentration in the plasma for 1-2 days. In contrast, troponin, which is a regulatory protein for muscle contraction, remains elevated for an extended period, often several days, following an MI.

User Zack Ream
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