Question

All of the following regarding Anti-A and Anti-B reagents used in forward typing for ABO typing are true except

A) They are monoclonal antibodies
B) They are used to detect the presence of A or B antigens on red blood cells
C) They react specifically with antigens on the surface of red blood cells
D) They are used in reverse typing for ABO blood grouping

Answer 1

The incorrect statement regarding Anti-A and Anti-B reagents is that they are used in reverse typing for ABO blood grouping; they are actually used in forward typing to detect A or B antigens on red blood cells.

Step-by-step explanation:

The statement regarding Anti-A and Anti-B reagents used in forward typing for ABO typing that is not true is: 'They are used in reverse typing for ABO blood grouping.' Forward typing involves using Anti-A and Anti-B reagents to detect the presence of A or B antigens on red blood cells.

This is done by mixing a blood sample with these monoclonal antibodies to see if agglutination (clumping) occurs, which would indicate a positive identification of the antigens. Reverse typing, on the other hand, uses the serum of the blood sample to check for the presence of antibodies against A and B antigens by mixing it with A and B cells.