Final answer:
The most suitable backup operation for a very large database made up of different files is Full Backup operation.
Step-by-step explanation:
For a very large database made up of different files, the most suitable backup operation would be the Full Backup operation. This type of backup operation creates a complete copy of all the files in the database.
Partial Backup operation only backs up specific parts of the database, which may not be ideal for a very large database. File Backup operation backs up individual files, but it may not capture the relationships between the files in the database.
Differential Backup operation backs up only the files that have changed since the last full backup, which can be useful for saving storage space and time. However, for a very large database, performing regular full backups is recommended to ensure comprehensive data protection.