Final answer:
The question is about items in The Binding of Isaac video game. Halo of Flies is the item that gives Isaac 2 orbital flies which block enemy shots, and when combined with two other fly items results in transforming into Lord of the Flies.
Step-by-step explanation:
The subject of this question pertains to the video game The Binding of Isaac. When it mentions 'Isaac' and 'orbital flies which block enemy shots,' it is referencing items within the game that can aid the player by providing defensive abilities or transformations.
The correct answer is B) Halo of Flies. Halo of Flies gives Isaac 2 orbital flies which block enemy shots, and collecting this along with two other fly-type items will trigger the transformation into Lord of the Flies within the game.
- The Mulligan does not provide orbiting flies.
- Forever Alone provides a distant blue fly that deals damage but doesn't block shots.
- Skatole changes the behavior of flies but does not provide orbiting ones.
Therefore, only Halo of Flies matches the description given in the question.