Final answer:
The nerves from the sacral plexus mainly extend to the upper posterior leg and continue down to provide innervation to the lower leg and foot.
Step-by-step explanation:
The two main destinations of the nerves from the sacral plexus are the posterior leg and the lower leg and foot. The sciatic nerve is the most significant systemic nerve from the sacral plexus, which is a combination of the tibial and fibular nerves. It extends across the hip joint and the gluteal region into the upper posterior leg. Furthermore, branches of the sciatic nerve, such as the tibial nerve, continue to provide innervation to the lower leg and foot.