Final answer:
The transmitter released by transmural stimulation in an isolated guinea-pig ileum preparation is acetylcholine (ACh). The subtype of receptor mediating the contractile response to ACh in this receptor is muscarinic receptor.
Step-by-step explanation:
The transmitter released by transmural stimulation in an isolated guinea-pig ileum preparation is acetylcholine (ACh). The subtype of receptor mediating the contractile response to ACh in this receptor is muscarinic receptor. The muscarinic receptor is a G protein-coupled receptor and does not exclusively cause depolarization of the postsynaptic membrane.