Final answer:
The 4-letter name of the state derived from the Iroquois word for "Great River" is Ohio, and the Trail of Tears involved the forced removal of the Cherokee tribe from Georgia to Oklahoma.
Step-by-step explanation:
The 4-letter name of the state that comes from an Iroquois word for "Great River" is Ohio (Option a). The name 'Ohio' is believed to be derived from the Iroquois word 'Ohi:yo', which means 'good river' or 'great river', referring to the Ohio River. The early presence of the Iroquois in the region influenced many place names, including the name of the state itself. The Trail of Tears involved the forced removal of the Cherokee tribe (Option d) from Georgia to Oklahoma. This was a result of the Indian Removal Act of 1830, which led to the relocation of several Native American tribes from the Southeastern United States.