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What is nuclear reprogramming and what is one concern? (separate definition and concern with a comma)

(a) The process is inefficient and does not always produce pluripotent cells.
(b) The reprogrammed cells may not be fully functional.
(c) The reprogrammed cells may be tumorigenic.
(d) The reprogrammed cells may be rejected by the patient's immune system.

User Antokhio
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Final answer:

Nuclear reprogramming refers to the process of transforming mature cells into pluripotent stem cells capable of differentiating into any cell type. However, there is a significant concern that the reprogrammed cells could be tumorigenic, carrying a risk of tumor formation.

Step-by-step explanation:

Nuclear reprogramming is a technique in regenerative medicine that aims to transform any cell of the body into a pluripotent stem cell that has the ability to differentiate into any type of cell. This reprogramming is achieved by introducing specific transcription factors that reset the mature cell's DNA to an embryonic state. It is a complex process that has the potential to treat age-related diseases and injury by creating patient-specific cells.

One Concern with Nuclear Reprogramming

Despite the promise of nuclear reprogramming, there are significant concerns associated with the technology. One concern is that the reprogrammed cells may be tumorigenic. In other words, there is a risk that cells that have been reprogrammed could develop into tumors, particularly if they are derived from adults with accumulated DNA mutations or if the reprogramming process itself introduces mutations. These cells exhibit unregulated cell division, akin to cancerous cells, potentially leading to tumors and cancers.

User Bela Vizy
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