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Where are microglia derived from, what is their job and where are they located?

User Gugod
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Final answer:

Microglia are derived from white blood cells and function as CNS-resident macrophages, clearing debris and pathogens, and recruiting immune cells via cytokine release.

Step-by-step explanation:

Microglia are a specialized type of glial cell within the central nervous system (CNS) that function similarly to macrophages in the rest of the body. Although their precise origin remains under investigation, it's suggested that they may derive from white blood cells, particularly macrophages, which integrate into the CNS during early development. Microglia are known for their role as the CNS-resident macrophages, essential for the immune system's defense mechanisms in the brain and spinal cord. They are involved in phagocytosing debris, foreign pathogens, and damaged cells, and also play a part in releasing cytokines to recruit other immune cells to sites of infection or injury. These cells are mobile and responsive, representing the first line of immune defense within the CNS environment.

User Muhammad Yasir
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