Question

A 24-year-old male with schizophrenia presents with fever, rigidity, and autonomic instability. What condition is most likely?

a) Neuroleptic malignant syndrome
b) Serotonin syndrome
c) Anticholinergic toxicity
d) Acute dystonic reaction

Answer 1

A 24-year-old male with schizophrenia presenting with fever, rigidity, and autonomic instability likely has Neuroleptic Malignant Syndrome, a severe reaction to antipsychotic medications characterized by several acute symptoms.

Step-by-step explanation:

A 24-year-old male with schizophrenia presenting with fever, rigidity, and autonomic instability is most likely suffering from Neuroleptic Malignant Syndrome (NMS). NMS is a life-threatening reaction to antipsychotic medications, which are commonly used to treat schizophrenia. The condition is characterized by hyperthermia, altered mental status, muscle rigidity, and autonomic dysfunction. These symptoms are thought to arise due to the blockade of dopamine receptors, which is the mechanism of action of many antipsychotic drugs. Prompt recognition and treatment are crucial for patients presenting with these symptoms.