Final answer:
GnRH is indeed released in a pulsatile manner by the hypothalamus, which is true. This pulsatile release is essential for the regulation of reproductive hormones such as LH and FSH.
Step-by-step explanation:
The statement that GnRH is released in a pulsatile manner by the hypothalamus is true. Gonadotropin-releasing hormone (GnRH) plays a key role in regulating the reproductive system. GnRH does indeed get released in pulses, and its secretion is influenced by the levels of estradiol in the body. High levels of estradiol stimulate the secretion, whereas low levels inhibit it. This pulsatile release is crucial for the proper function of the hormones LH and FSH, which are also part of the regulatory system that controls the ovarian and menstrual cycles.
For example, in females, the release of GnRH stimulates the production of FSH and LH, which in turn regulate the menstrual cycle. The pulsatile release of GnRH is essential for the proper functioning of the reproductive system.