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What is the link between phagophores and degradation?

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Final answer:

The link between phagophores and degradation is found in the process of phagocytosis where a phagocyte engulfs a pathogen, resulting in its breakdown within a phagolysosome that contains digestive enzymes and acids, followed by exocytosis of waste.

Step-by-step explanation:

The link between phagophores and degradation lies in the process of phagocytosis, which involves cellular digestion and destruction of pathogens. When a pathogen such as a bacterium is detected, a phagocyte generates a phagophore that extends from its plasma membrane to envelop the pathogen, creating a phagosome. This phagosome then combines with a lysosome to form a phagolysosome, where hydrolytic enzymes from the lysosome degrade the captured pathogen. The final steps involve the breakdown of the pathogen and the excretion of the residual waste from the cell through exocytosis.

Additionally, phagocytosis plays a crucial role in the immune response where dendritic cells capture pathogens for antigen processing. Proteases are key in this process, as they break down proteins for presentation to T cells. Lastly, understanding the catabolic pathways, including beta-oxidation for lipids and proteases for proteins, illustrates how microbes contribute to the degradation of various macromolecules, eventually feeding into glycolysis and the Krebs cycle.

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