Final answer:
ATP-dependent chaperones require ATP to function, while ATP-independent chaperones do not require ATP.
Step-by-step explanation:
ATP-dependent chaperones and ATP-independent chaperones are two types of protein helpers that assist in the folding process of proteins. The difference between them lies in their dependence on ATP.
ATP-dependent chaperones require ATP to function. They use the energy from ATP hydrolysis to facilitate protein folding and prevent aggregation of polypeptides. Examples of ATP-dependent chaperones include Hsp70 and Hsp90.
ATP-independent chaperones, on the other hand, do not require ATP for their function. They rely on other energy sources or molecular mechanisms to assist in protein folding. One example of an ATP-independent chaperone is the chaperonin GroEL/GroES.