Final answer:
Osler-Weber-Rendu syndrome increases the risk for intracranial malformations due to its impact on blood vessel formation.
Step-by-step explanation:
Inheritance of Osler-Weber-Rendu syndrome, also known as Hereditary Hemorrhagic Telangiectasia (HHT), does put individuals at risk for intracranial malformations, such as arteriovenous malformations. This genetic disorder affects blood vessel formation and can lead to various complications, including nosebleeds, skin telangiectasias, and potentially serious blood vessel malformations in organs like the brain, liver, and lungs. Hence, the correct answer to whether individuals with Osler-Weber-Rendu syndrome are at risk for intracranial malformations is True.