Final answer:
During anaphase of mitosis, seperase cleaves the protein complex that holds sister chromatids together, allowing them to separate at the centromere. This ensures that the two new daughter cells will contain identical genetic material.
Step-by-step explanation:
Anaphase is the point in mitosis at which seperase cleaves the protein complex that holds sister chromatid pairs together. Seperase is kept in an inactive state until it is needed in normal cells.
During anaphase, the cohesin proteins degrade, allowing the sister chromatids to separate at the centromere. Each chromatid, now called a chromosome, is pulled rapidly toward the centrosome to which its microtubule is attached. This ensures that the two new daughter cells will contain identical genetic material.