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What are the clinical features of familial fatal insomnia?

User Jkaufmann
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Final answer:

Familial Fatal Insomnia (FFI) features severe insomnia, neuropsychiatric symptoms, autonomic dysfunction, and physical decline. While there is no cure, treatment focuses on symptom management, and recognizing early symptoms is vital for seeking care and improving outcomes. Other sleep disorders include parasomnias, sleep apnea, and narcolepsy.

Step-by-step explanation:

Familial Fatal Insomnia (FFI) is a rare inherited prion disease that affects the sleep-wake cycle and leads to progressive neurodegeneration. Some of the clinical features of FFI include:

  • Severe insomnia: Patients have difficulty falling asleep and experience progressively worsening insomnia.
  • Autonomic dysfunction: This includes profuse sweating, increased heart rate, and high blood pressure.
  • Motor abnormalities: Patients may develop abnormal movements, such as twitching.
  • Psychiatric symptoms: Individuals with FFI may experience hallucinations, delusions, and changes in mood and behavior.

Fatal familial insomnia is characterized by a gradual loss of the ability to sleep, which eventually leads to a complete inability to sleep and severe neurological symptoms. If you suspect you or someone you know may have FFI, it is essential to seek medical attention for proper diagnosis and management.

User Jlehr
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