Final answer:
Typically, a host will not have multiple species of prions present simultaneously, as prion disease arises from a single prion protein misfolding and multiplying its abnormal form.
Step-by-step explanation:
It is not typical for multiple distinct species of prions to be present in a host simultaneously. Prions are misfolded proteins that can cause other proteins, particularly their properly folded counterparts, within their host to adopt the same misfolded structure. The damage wrought by prions is highlighted in diseases like Creutzfeldt-Jakob disease (CJD), Mad Cow Disease, and Scrapie in sheep. Since prions are essentially rogue versions of normal proteins, the diversity of prion forms within a host would be contingent upon the variety of the normal prion protein gene mutations or if multiple misfolded prions were somehow introduced to the host, which is highly uncommon. Most prion diseases arise from a single misfolded prion protein variant propagating its abnormal structure.