Final Answer:
This type of RNAi is called endogenous RNAi, which skips Drosha and DGCR8, utilizing the spliceosome to cleave the hairpin structure, resulting in pre-miRNA without extraneous sequences.
Step-by-step explanation:
Endogenous RNA interference (RNAi) is a unique mechanism in which the cell employs the spliceosome, a complex involved in RNA splicing, to process hairpin structures directly. Unlike the canonical pathway involving Drosha and DGCR8, endogenous RNAi streamlines the process, yielding pre-miRNA without additional sequences. This pathway is essential for the generation of mature microRNAs (miRNAs), small RNA molecules that play crucial roles in post-transcriptional gene regulation.
Understanding the diverse pathways of RNA interference provides insights into the complexity of gene expression regulation. Exploring the nuances of endogenous RNAi sheds light on alternative mechanisms cells use to control gene expression and maintain cellular homeostasis.