Question

this process involves UP-frameshift proteins (UPFs: UPF1, UPF2 and UPF3) -this process relies on reversible phosphorylation of UPF1 (switch) happens during a pioneer round of translation, likely so that aberrant transcripts are eliminated before mass translation is engaged

Answer 1

The process involves UPF proteins in translation and relies on reversible phosphorylation of UPF1 to eliminate aberrant transcripts.

Step-by-step explanation:

The process in question is related to translation, which is a step in protein synthesis. During translation, UPF proteins (UPF1, UPF2, and UPF3) are involved in eliminating aberrant transcripts before mass translation occurs. The process relies on reversible phosphorylation of UPF1. Phosphorylation of UPF1 prevents it from binding to GTP, thus impeding the formation of the initiation complex and hindering translation.