Final answer:
The statement is false; eukaryotic transcription termination involves different mechanisms for the various RNA polymerases, and prokaryotic transcription termination occurs through specific sequences. Eukaryotic transcription is followed by extensive RNA processing, which does not occur in prokaryotes.
Step-by-step explanation:
The statement "only 1 RF needed for chain termination in eukaryotes, 2 RFs in prokaryotes" is false when referring to RNA polymerase during transcription termination. In eukaryotes, the termination of transcription involves different mechanisms for each of the three RNA polymerases. For example, RNA Polymerase II transcribes a tail beyond the end of the gene, which is then processed, while RNA Polymerase I and III require specific sequences or structures for termination. In prokaryotes, genes are often polycistronic, and transcription terminates when the RNA polymerase encounters specific sequences that lead to the release of the RNA transcript.
Eukaryotic transcription is more complex, involving additional steps of RNA processing that are not needed in prokaryotic transcription. Furthermore, due to the lack of a nucleus in prokaryotes, transcription and translation can occur concurrently, which is not possible in eukaryotes.