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What allows for fast postsynaptic responses in pre- to post-ganglionic transmission?

a) Voltage-gated sodium channels
b) G-protein coupled receptors
c) Nitric oxide
d) Acetylcholinesterase

2 Answers

3 votes

Final answer:

Fast postsynaptic responses are facilitated by voltage-gated sodium channels that quickly open upon neurotransmitter binding, allowing Na+ ions to enter the postsynaptic cell and potentially trigger an action potential.

Step-by-step explanation:

The fast postsynaptic responses in pre- to post-ganglionic transmission are enabled by voltage-gated sodium channels. When a neurotransmitter, such as acetylcholine, binds to ligand-gated ion channels at the neuromuscular junction, it results in the opening of these channels. The subsequent rapid diffusion of Na+ ions into the postsynaptic cell creates an action potential, leading to a cellular response like muscle contraction. Ligand-gated ion channels allow for a quick depolarization of the postsynaptic membrane, generating an excitatory postsynaptic potential (EPSP) which can trigger an action potential if the depolarization threshold is reached.

User Harre
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7 votes

Final answer:

Voltage-gated sodium channels are responsible for the fast postsynaptic responses in pre- to post-ganglionic transmission, allowing sodium ions to enter the postsynaptic cell and trigger an action potential.

Step-by-step explanation:

The fast postsynaptic responses in pre- to post-ganglionic transmission are enabled primarily by voltage-gated sodium channels. When acetylcholine, the neurotransmitter released at the neuromuscular junction, binds to ligand-gated ion channels on the postsynaptic membrane, it results in the opening of these channels. Subsequently, sodium ions (Na+) rush into the postsynaptic cell, leading to depolarization and the generation of an action potential, which can then trigger muscle contraction and other rapid cellular responses.

User Jeffrey Basurto
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8.7k points