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What is the likely mechanism underlying the opening of ion channels in afferent muscle spindle nerve fibres?

a) Voltage-gated channels
b) Ligand-gated channels
c) Mechanical stretch
d) Temperature-dependent channels

1 Answer

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Final answer:

The opening of ion channels in afferent muscle spindle nerve fibers is likely due to mechanical stretch. These channels respond to physical distortion of the cell membrane caused by stretching, which triggers an action potential for sensory signaling.

Step-by-step explanation:

The likely mechanism underlying the opening of ion channels in afferent muscle spindle nerve fibers is mechanical stretch. These ion channels, known as mechanically gated channels, open due to a physical distortion of the cell membrane. The muscle spindles are sensitive to stretch; when they are mechanically stimulated, the ion channels open, allowing ions to enter or exit the cell. This process is crucial for the initiation of sensory signals that inform the central nervous system about muscle length and the rate of change in length.

For example, mechanosensitive ion channels are connected to the plasma membrane and the cytoskeleton by hair-like tethers. When there is mechanical pressure, such as the stretching of muscles during movement, these channels are physically opened, causing ions to flow through and generate an action potential. This response is similar to mechanoceptors found in the skin and also the mechanosensitive channels connected to stereocilia in the human ear, which help transduce sound waves into nerve signals.

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