Final answer:
Nicotine is considered the most physically addictive drug. It exerts its effects through nicotinic acetylcholine receptors and leads to withdrawal symptoms when not consumed.
Step-by-step explanation:
The correct statement about tobacco and addiction is that some researchers believe nicotine is the most physically addictive of all drugs. Nicotine is the active chemical in tobacco, and it exerts its effects through the agonism of nicotinic acetylcholine receptors.
It increases the activity of dopaminergic neurons in the brain's reward system, leading to addiction. Nicotine withdrawal symptoms include cravings, headaches, irritability, anxiety, decreased heart rate, and high blood pressure.