Final answer:
While we do not have the precise count, the information provided suggests that several counties in California, including those in the Los Angeles CSA and Santa Clara, had populations well over 500,000 in 2010.
Step-by-step explanation:
The question asks how many counties in California had a population of more than 500,000 persons as of the 2010 census. Considering the provided reference information regarding population by district and county-level populations, we can deduce relevant data about county populations. Specifically, if each State Assembly District in 2011 had between 461,000 and 470,000 people, and districts are designed to have comparable populations, this can be used as an approximate lower benchmark for the populations of California's most populous counties.The reference to Los Angeles being the anchor for a massive Combined Statistical Area (CSA) with over 18 million people, including several counties such as Ventura, Orange, Los Angeles, San Bernardino, and Riverside, also indicates that each of these counties has populations far exceeding 500,000. Information provided for specific counties like Santa Clara with documented cases of a disease also implies a significant population well above the 500,000 threshold. Hence, we can infer that several of California's counties, likely including those mentioned as part of Los Angeles's CSA and others like Santa Clara, had populations exceeding 500,000 in 2010.In conclusion, while the provided information does not give an exact count of counties with over 500,000 people, it clearly suggests that multiple counties, including but not limited to Ventura, Orange, Los Angeles, San Bernardino, Riverside, and Santa Clara, exceeded this population number by 2010.