Final answer:
The endocrine system releases hormones into the bloodstream, which bind to receptors on or in target cells. Steroids are lipid-soluble hormones that can bind to intracellular receptors in target cells.
Step-by-step explanation:
The endocrine system is a system of glands that release chemical messenger molecules called hormones into the bloodstream. Hormones bind to receptors on or in the plasma membrane of target cells. This binding initiates a response within the cell. Steroids are lipid-soluble hormones that can diffuse across the plasma membrane and bind to intracellular receptors in the cytoplasm or nucleus of target cells.