Final answer:
Between 1600 and 1650, approximately 80% of the indigenous population of the Americas died due to European-borne diseases such as smallpox, measles, and flu viruses.
Step-by-step explanation:
The European-borne smallpox, measles, and flu viruses had a devastating impact on the indigenous peoples of the Americas between the years 1600 and 1650. It is estimated that approximately 80% of the indigenous population of South, Central, and North America perished as a result of these diseases. This percentage is equivalent to tens of millions of people.