Final answer:
General transcription factors recognize the promoter sequence and recruit RNA polymerase II to initiate transcription in RNA polymerase II mediated transcription. These general transcription factors, such as TFIID, TFIIB, and others, bind to specific regions on the DNA called promoter sequences, including the TATA box.
Step-by-step explanation:
The roles of general transcription factors in RNA polymerase II mediated transcription are to recognize the promoter sequence on the DNA and recruit RNA polymerase II to initiate transcription. These general transcription factors, such as TFIID, TFIIB, and others, bind to specific regions on the DNA called promoter sequences, including the TATA box. Additionally, other transcription factors may bind to enhancer regions to increase or prevent transcription. Once all the transcription factors and RNA polymerase II are bound, they form the transcription initiation complex and begin making the mRNA.
The major general transcription factors involved in RNA Pol II-mediated transcription include TFIIA, TFIIB, TFIID, TFIIE, TFIIF, and TFIIH. These factors, along with RNA Pol II, orchestrate the complex process of transcription initiation and ensure the accurate and regulated synthesis of mRNA. These general transcription factors, such as TFIID, TFIIB, and others, bind to specific regions on the DNA called promoter sequences, including the TATA box. The recruitment and assembly of these factors at the promoter region are critical for the proper functioning of the transcription machinery.