Final answer:
Neurotransmitters such as endorphins and biogenic amines like serotonin, contribute to feelings of tranquility and pain relief in the body. Endorphins are particularly noted for their role in creating a 'runner's high' and reducing pain, while biogenic amines are involved in mood regulation and can be influenced by antidepressant medications.
Step-by-step explanation:
The naturally occurring neurotransmitters in the body that contribute to tranquil feelings and pain suppression are known as endorphins and a group called biogenic amines, which includes serotonin, norepinephrine, and dopamine. Serotonin, derived from the amino acid tryptophan, is significant in the central nervous system (CNS) for its role in mood regulation and its association with feelings of well-being. Furthermore, endorphins are released during activities such as exercise, excitement, and sex, not only reducing pain but also inducing euphoria.
Neurotransmitters can be excitatory or inhibitory, like serotonin or gamma-aminobutyric acid (GABA), influencing the likelihood of an action potential in the postsynaptic neuron. Endorphins, particularly during strenuous physical activities, can lead to a 'runner's high,' highlighting their significant impact on pain and emotion management. Antidepressants are medications that help normalize serotonin levels, thereby managing symptoms of depression.