Question

What happens if chromosomes are not properly attached to the spindle at the M phase?

A) Cell enters G0 phase
B) Cell proceeds to cytokinesis
C) Cell undergoes apoptosis
D) Cell proceeds to S phase

Answer 1

If chromosomes are not properly attached to the spindle at the M phase, the cell cycle will not proceed until the kinetochores of each pair of sister chromatids are firmly anchored to at least two spindle fibers arising from opposite poles of the cell.

Step-by-step explanation:

If chromosomes are not properly attached to the spindle at the M phase, the cell cycle will not proceed until the kinetochores of each pair of sister chromatids are firmly anchored to at least two spindle fibers arising from opposite poles of the cell. This is known as the M checkpoint or spindle checkpoint. If the chromosomes are not properly attached, the cell will halt the cycle and attempt to remedy the issue before proceeding.