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Brown adipocytes contain thermogenin, a protein that works by

A) Inhibiting cellular respiration
B) Enhancing ATP production
C) Facilitating lipid synthesis
D) Uncoupling oxidative phosphorylation

User Charod
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1 Answer

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Final answer:

Thermogenin in brown adipocytes aids in heat production by uncoupling oxidative phosphorylation instead of producing ATP, thus the correct response is D) Uncoupling oxidative phosphorylation.

Step-by-step explanation:

The protein thermogenin found in brown adipocytes plays a critical role in the process of non-shivering thermogenesis, which is the production of heat without muscular movements. Thermogenin, also known as uncoupling protein 1 (UCP1), operates by uncoupling oxidative phosphorylation. Instead of energy from the electron transport chain being used to generate adenosine triphosphate (ATP), the process results in the generation of heat.

Brown adipose tissue, which is highly vascularized and contains mitochondria packed with the protein thermogenin, is specialized for this heat production. When the body is exposed to cold temperatures, brown adipose tissue is activated, leading to the oxidation of fatty acids. However, this oxidation does not culminate in the production of ATP as it would in typical cellular respiration. Instead, due to the action of thermogenin, a proton (H+) gradient is dissipated as heat, effectively warming the body without producing significant amounts of ATP.

Thus, the correct answer to the student's question is D) Uncoupling oxidative phosphorylation, as thermogenin decreases the production of ATP while increasing the production of heat.

User Rlc
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