75.8k views
0 votes
In dosage compensation:

a) An X chromosome can be inactivated.
b) Gene expression can be increased from a single X chromosome.
c) Gene expression can be reduced from a pair of X chromosomes.
d) All of the above are possible

User Couitchy
by
8.0k points

1 Answer

4 votes

Final answer:

In dosage compensation, X chromosome inactivation (a Barr body), upregulation of gene expression from a single X chromosome, and potential reduction in gene expression from both X chromosomes in females are mechanisms used to ensure gene expression levels are equivalent between sexes; therefore, all listed methods (a, b, and c) are possible.

Step-by-step explanation:

In dosage compensation, various mechanisms ensure that the amount of gene expression from the X chromosomes is relatively equal between males and females, despite females having two X chromosomes and males having only one. These mechanisms include:

  • a) X chromosome inactivation: In females, one of the two X chromosomes is epigenetically inactivated in somatic cells, forming what is known as a Barr body. This process ensures that females have similar X chromosome gene expression levels to males, who possess only a single X chromosome.
  • b) Gene expression increase from a single X chromosome: In organisms like Drosophila, gene expression from the single active X chromosome in males is upregulated to match the level of females.
  • c) Gene expression reduction from a pair of X chromosomes: Although not typically referred to in standard dosage compensation, theoretically, the expression could also be reduced in both X chromosomes in females to achieve balance with males.

Overall, the correct answer to the question is d) All of the above are possible.

User Krystina
by
8.1k points