Question

An individual of karyotype 47, +13 has which of the following syndromes?

a. Down syndrome
b. Turner syndrome
c. Patau syndrome
d. Klinefelter syndrome

Answer 1

An individual with a karyotype of 47, +13 has Patau syndrome, which is characterized by an extra chromosome 13. This is different from the conditions caused by extra copies of other chromosomes like chromosome 21 in Down syndrome or sex chromosome variations in Turner syndrome and Klinefelter syndrome.

Step-by-step explanation:

The individual with a karyotype of 47, +13 has an extra chromosome 13. This condition is known as Patau syndrome. People with Patau syndrome have severe intellectual disability and physical abnormalities in many parts of the body.

Individuals with Down syndrome have an extra chromosome 21, also known as trisomy 21. Turner syndrome occurs in females who typically have a single X chromosome (45, X) instead of two sex chromosomes. Klinefelter syndrome is characterized by males having an extra X chromosome, typically resulting in an XXY karyotype (47, XXY).

Therefore, the correct answer is c. Patau syndrome. This is due to the nondisjunction of chromosome 13, not chromosome 21 which leads to Down syndrome, or the sex chromosomes which are involved in Turner syndrome and Klinefelter syndrome.