84.7k views
5 votes
Women known to be heterozygous or carriers for the sex-linked recessive condition of hemophilia A were studied to determine the time required for their blood to clot. It was found that the time required for their blood to clot varied from individual to individual. The values obtained ranged from normal clotting at one extreme to clinical hemophilia at the other extreme. What is the most probable CORRECT explanation for these findings?

a) Hemophilia A is a dominant trait.

b) Hemophilia A is a recessive trait.

c) Incomplete penetrance of the hemophilia A allele.

d) Codominance between the normal and hemophiliac alleles.

1 Answer

2 votes

Final answer:

The most probable correct explanation for the variation in blood clotting time among women heterozygous or carriers for the sex-linked recessive condition of hemophilia A is that Hemophilia A is a recessive trait.

Correct answer is b. Hemophilia A is a recessive trait.

Step-by-step explanation:

The most probable correct explanation for the variation in blood clotting time among women heterozygous or carriers for the sex-linked recessive condition of hemophilia A is that Hemophilia A is a recessive trait.

When it comes to sex-linked traits like hemophilia, the allele for the condition is located on the X chromosome. Since females have two X chromosomes, they need to inherit two copies of the defective gene to manifest the disease. Females who inherit only one copy of the defective gene are carriers of the condition but typically do not show symptoms of hemophilia. On the other hand, males are more likely to be affected by hemophilia because they have only one X chromosome. If they inherit the defective gene, they do not have another copy to compensate for it.

In this case, the variation in clotting time among the women studied indicates that some of them have inherited one normal allele and one hemophiliac allele, making them carriers, while others have inherited two copies of the normal allele, resulting in normal clotting. At the other extreme, some women have inherited two copies of the hemophiliac allele, resulting in clinical hemophilia.

Therefore, the most probable correct explanation for the variation in blood clotting time observed in the study is option b. Hemophilia A is a recessive trait.

User Rahul Kumar
by
8.5k points