Question

Place these steps in a simplified model for transcriptional activation of a eukaryotic gene in order from first to last.

a) Chromatin remodeling, RNA polymerase binding, Transcription initiation, mRNA synthesis
b) RNA polymerase binding, Chromatin remodeling, Transcription initiation, mRNA synthesis
c) Transcription initiation, Chromatin remodeling, RNA polymerase binding, mRNA synthesis
d) Chromatin remodeling, Transcription initiation, RNA polymerase binding, mRNA synthesis

Answer 1

The correct order of steps for transcriptional activation of a eukaryotic gene is RNA polymerase binding, Chromatin remodeling, Transcription initiation, mRNA synthesis.

Step-by-step explanation:

The correct order of steps in a simplified model for transcriptional activation of a eukaryotic gene is b) RNA polymerase binding, Chromatin remodeling, Transcription initiation, mRNA synthesis.

In eukaryotic transcription, RNA polymerase binds to the gene's promoter region after transcription factors have bound to the promoter sequence. Chromatin remodeling then occurs to loosen the DNA structure, allowing for transcription initiation. Finally, mRNA synthesis takes place, where RNA polymerase adds nucleotides to the mRNA strand.