Question

A technique called Comparative Genomic Hybridization (CGH) can be used to determine whether a cancer cell has changes in chromosome structure, such as duplications or deletions.

a) Comparative Genomic Hybridization (CGH) analyzes gene expression changes in cancer cells.

b) CGH is a technique for detecting alterations in chromosome structure, such as duplications or deletions, in cancer cells.

c) CGH is a method to determine the protein profiles of cancer cells.

d) CGH is used to study the metabolic changes in cancer cells.

Answer 1

Comparative Genomic Hybridization (CGH) is a technique used to detect alterations in chromosome structure in cancer cells. It involves comparing the DNA from cancer cells to a reference DNA sample and can help identify chromosomal abnormalities in cancer cells.

Step-by-step explanation:

Comparative Genomic Hybridization (CGH) is a technique used to detect alterations in chromosome structure, such as duplications or deletions, in cancer cells. It is not used to analyze gene expression changes, determine protein profiles, or study metabolic changes in cancer cells.

CGH involves comparing the DNA from cancer cells to a reference DNA sample. By labeling the cancer DNA with one color and the reference DNA with another color, researchers can identify changes in chromosome structure based on the intensity of the colors. This technique is helpful in understanding the genetic basis of cancer and identifying potential targets for therapy.

Overall, CGH is a valuable tool in cancer research and diagnostics, providing important information about chromosomal abnormalities in cancer cells.