Final answer:
David Hume's epistemology was based on skepticism and empiricism, challenging traditional notions of knowledge.
Step-by-step explanation:
David Hume's epistemology was based on the idea of skepticism and empiricism. Hume believed that all our knowledge comes through the senses and that our perceptions are our thoughts. He argued that reasoning alone does not lead to knowledge and that sense impressions are not proof of an external independent reality. Hume's skepticism and empiricism challenged traditional notions of knowledge and influenced later philosophers such as Immanuel Kant.