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DDAVP for bleeding or pre-op. Replace factor VIII (contains vWF) if bleeding continues.

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Final answer:

Factor VIII is important for blood clotting and forms a complex with von Willebrand factor. In bleeding or pre-op situations, replacement therapy with factor VIII containing vWF is recommended.

Step-by-step explanation:

Factor VIII plays a crucial role in the blood clotting process. It is responsible for binding to von Willebrand factor (vWF) and forming a complex that helps stabilize clot formation.

In bleeding or pre-op situations, if there is a deficiency of factor VIII or the bleeding continues despite treatment, replacement therapy with factor VIII-containing vWF is recommended. This helps restore the missing clotting factor and facilitates the formation of stable clots.

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